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FASEB J 31(11):46654681 Kleinman HK, Martin, GR (2005) Matrigel: basement membrane matrix with biological activity

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These studies suggest that resveratrol might serve as an effective approach to improve ovarian functions and delay ovarian aging, and its specific effects and mechanisms are as follows: 1) increases nuclear factor erythroid 2-related factor 2 (Nrf2), a redox-sensitive transcription factor that regulates the expression of antioxidant genes (Espinosa-Diez et al., 2015), total glutathione (tGSH), SOD, and SOD2

Limitations and future directions As with any animal study, the limitation of the current study is the application of its findings to human settings, which is challenging due to both obvious and subtle distinctions between humans and animals